The purpose of the Njernda Partnership Model is to support a partnership approach that aims to improve the health status of local Aboriginal people in the Campaspe and Murray areas. The social and political context of 2010 led to the establishment of the Campaspe Aboriginal Health Partnership Group, chaired by the Njernda Aboriginal Corporation. The model implemented by the Group’s membership has led to significant improvements in the provision of culturally sensitive health care by mainstream organisations, and has successfully developed interventions that address the social determinants of health.